منابع مشابه
Osteopoikilosis: a rare cause of bone pain
Background: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. We present a case of 34-year-old man suffering from polyarthralgia an...
متن کاملA Review on Experimental Assessments of Pain Threshold in Healthy Human Subjects
A B S T R A C T There are three types of nerve fibers that are involved in the transmission of pain stimuli: C fibers (slower fibers) for thermal, mechanical and chemical stimuli, A-delta fibers for thermal or mechanical stimuli and A-beta fibers for touch stimuli. Clinically, this is crucial in making an accurate assessment of the pain level experienced by a suffering patient, in indicating th...
متن کاملAntinociceptive Effect of Intrathecal Microencapsulated Human Pheochromocytoma Cell in a Rat Model of Bone Cancer Pain
Human pheochromocytoma cells, which are demonstrated to contain and release met-enkephalin and norepinephrine, may be a promising resource for cell therapy in cancer-induced intractable pain. Intrathecal injection of alginate-poly (l) lysine-alginate (APA) microencapsulated human pheochromocytoma cells leads to antinociceptive effect in a rat model of bone cancer pain, and this effect was block...
متن کاملProduction, Quality Control and Pharmacokinetic Studies of 177Lu-EDTMP for Human Bone Pain Palliation Therapy Trials
Developing new bone pain palliation agents is a mandate in handling end-stage cancer patients around the world. Possibly, Lu-177 ethylenediaminetetramethylene phosphonic acid (177Lu-EDTMP) is a therapeutic agent which can be widely used in bone palliation therapy. In this study, 177Lu-EDTMP complex was prepared successfully using synthesized EDTMP ligand and 177LuCl3. Lu-177 chloride was obt...
متن کاملA Novel Multimodal Model to Evoke and Modulate Human Experimental Rectosigmoid Pain Psychophysical and Neurophysiological Studies
A novel multimodal model to evoke and modulate human experimental rectosigmoid pain Brock, Christina Citation for published version (APA): Brock, C. (2009). A novel multimodal model to evoke and modulate human experimental rectosigmoid pain: psychophysical and neurophysiological studies. General rights Copyright and moral rights for the publications made accessible in the public portal are reta...
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ژورنال
عنوان ژورنال: Basic & Clinical Pharmacology & Toxicology
سال: 2012
ISSN: 1742-7835
DOI: 10.1111/bcpt.12002